Our services incorporate the most recent scientific insights in pharmacokinetics (PK) and pharmacodynamics (PD), with the focus on modelling and simulation.

Modelling & Simulation:

• Population-type (nonlinear mixed-effects) modelling
  (PK and PK-PD)
• Disease progression analysis for quantitative and qualitative evaluation of drug effects
• Simulation studies, Computer Assisted Trial Design (CATD), Clinical Trial Simulation (CTS), and sampling scheme optimisation
• Physiologically-based PK (PB-PK) modelling
• Continuous, categorical responses, and time-to-event data
• Preclinical and clinical data
• Covariate analysis and interpretation
• Small and large molecules
• Extrapolation: in vitro-in vivo , preclinical to clinical, interspecies, adults to paediatrics

Additional Services:

• Education and Training (General and 'Tailor-made' courses)
• Regulatory Submission Support (Expert Reports, Assistance at hearings)
• Presentation at conferences and meetings
• Preparation of Publications