Publications
2011
Diack C., Ackaert O., Ploeger B.A., Graaf P.H.v.d., Gurrell R., Ivarsson M. and Fairman D., A hidden Markov model to assess drug-induced sleep fragmentation in the telemetered rat, J Pharmacokinet Pharmacodyn, 10: 10, 2011....[more]
2011
Erp N.P.v., Guchelaar H.J., Ploeger B.A., Romijn J.A., Hartigh J. and Gelderblom H., Mitotane has a strong and a durable inducing effect on CYP3A4 activity, Eur J Endocrinol., 164(4): 621-626. Epub 2011 Jan 2010., 2011....[more]
2011
Holford N., Ma S.C. and Ploeger B.A., Response to "validation and assessment of predictive performance in simulation models of clinical trials", Clin Pharmacol Ther., 89(4): 488...[more]
2011
Krekels E.H., Jongh J.d., Lingen R.A.v., Marel C.D.v.d., Choonara I., Lynn A.M., Danhof M., Tibboel D. and Knibbe C.A., Predictive performance of a recently developed population pharmacokinetic model for morphine and its...[more]
2010
Holford N., Ma S.C.and Ploeger B.A. Clinical Trial Simulation: A Review, Clin Pharmacol Ther. 7:7, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20613720[more]
2010
Muller A.E., Mouton J.W., Oostvogel P.M., Dorr P.J., Voskuyl R.A., Jongh J.d., Steegers E.A. and Danhof M., The pharmacokinetics of clindamycin in pregnant women in the peripartum period, Antimicrob Agents Chemother, 2010....[more]
2010
Benson N, Snelder N, Ploeger B, Napier C, Sale H, Birdsall NJ, Butt RP, van der Graaf PH. Estimation of binding rate constants using a simultaneous mixed-effects method: application to monoamine transporter reuptake...[more]
2010
Zwiers A., Heuvel M.v.d., Smeets J. and Rutherford S., Assessment of the Potential for Displacement Interactions with Sugammadex: A Pharmacokinetic-Pharmacodynamic Modelling Approach, Clin Drug Investig, 10(10):...[more]
2010
Steeg T.J.v., Krekels E.H., Freijer J., Danhof M. and Lange E.C.d., Effect of altered AGP plasma binding on heart rate changes by S(-)-propranolol in rats using mechanism-based estimations of in vivo receptor affinity...[more]
2010
Press R.R., Ploeger B.A., Hartigh J.d, Straaten T.v.d., van Pelt H., Danhof M., Fijter H.d. and Guchelaar H.J., Explaining variability in ciclosporin exposure in adult kidney transplant recipients, Eur J Clin Pharmacol., 66(6):...[more]